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Status |
Public on Jul 27, 2021 |
Title |
Impaired Right Ventricular Calcium Cycling Is an Early Risk 2 Factor in R14del-Phospholamban Arrhythmias |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We utilized humanized wild-type and R14 deletion (R14del) phospholamban (PLN) knock-in mice to determine the role of the inherited PLN-R14del on malignant right ventricular arrhythmias.
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Overall design |
RNA-seq to determine global gene expression profiles in LV and RV samples from humanized WT and R14del mutant mouse hearts
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Contributor(s) |
Tranter M, Kranias L |
Citation(s) |
34204946, 36375644 |
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Submission date |
May 01, 2021 |
Last update date |
Nov 17, 2022 |
Contact name |
Michael Tranter |
E-mail(s) |
[email protected]
|
Organization name |
The Ohio State University
|
Department |
Molecular Medicine and Therapeutics
|
Street address |
2255 Kenny Road
|
City |
Columbus |
State/province |
OH |
ZIP/Postal code |
43210 |
Country |
USA |
|
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Platforms (1) |
GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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Samples (12)
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Relations |
BioProject |
PRJNA726640 |
SRA |
SRP318085 |