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| Status |
Public on Sep 29, 2009 |
| Title |
Preliminary characterization of gene expression in European wild boar naturally infected with Brucella suis |
| Organism |
Sus scrofa |
| Experiment type |
Expression profiling by array
|
| Summary |
Brucella suis infects macrophages and dendritic cells. Wild boars act as reservoirs and carriers of Brucella suis biovar 2, and there is evidence that wild boar can be the main source of infection for domestic pigs through the venereal route. Transmission through this route could be an important path for disesease dissemination. The result from this study will contribute to the overall understanding of the molecular pathogenic mechanisms involved during Brucella suis infection in European wild boar.
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| Overall design |
In this study we preliminarily characterized differential gene expression in European wild boar naturally infected with Brucella suis biovar 2 using Microarray hybridization and Real Time RT-PCR analysis. Since Brucella suis acts by infecting macrophages, we used spleen cells to analyze the gene expression response to Brucella suis infection.
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| Contributor(s) |
Galindo RC, Marín C, Muñoz PM, Blasco J, Gortázar C, Kocan KM, de la Fuente J |
| Citation(s) |
21115167 |
| |
| Submission date |
Aug 04, 2009 |
| Last update date |
May 03, 2013 |
| Contact name |
Ruth Cecilia Galindo |
| Organization name |
Instituto de Investigacion en Recursos Cinegéticos
|
| Department |
Animal Health
|
| Lab |
Genomic
|
| Street address |
Ronda de Toledo s/n
|
| City |
Ciudad Real |
| State/province |
Ciudad Real |
| ZIP/Postal code |
13005 |
| Country |
Spain |
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| Platforms (1) |
| GPL3533 |
[Porcine] Affymetrix Porcine Genome Array |
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| Samples (6)
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| GSM436122 |
Negative control sample 283 |
| GSM436123 |
Brucella suis uninfected 353 European wild boar sample |
| GSM436124 |
430 European wild boar infected sample with Brucella suis |
| GSM436125 |
487 European wild boar sample infected with Brucella suis |
| GSM436126 |
355 Brucella suis infected sample from European wild boar |
| GSM436127 |
535 uninfected European wild boar sample |
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| Relations |
| BioProject |
PRJNA118697 |
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