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Series GSE17574 Query DataSets for GSE17574
Status Public on Jul 09, 2010
Title Statin-induced Myopathy
Organism Homo sapiens
Experiment type Genome variation profiling by SNP array
Summary We performed a genome-wide association study in pooled DNA samples from patients with severe statin myopathy and persistent symptoms post-therapy versus pooled DNAs from an age-adjusted statin-tolerant group.
 
Overall design Affymetrix 100K SNP arrays were used according to the manufacturers instructions with two pools of 19 and 20 statin myopathy patients and two pools of 20 statin-tolerant controls.
 
Contributor(s) Isackson PJ
Citation(s) 21826682
Submission date Aug 10, 2009
Last update date Nov 01, 2019
Contact name Paul J. Isackson
E-mail(s) [email protected]
Organization name University at Buffalo
Department Pediatrics
Street address 100 High St
City Buffalo
State/province NY
ZIP/Postal code 14203
Country USA
 
Platforms (2)
GPL2004 [Mapping50K_Hind240] Affymetrix Human Mapping 50K Hind240 SNP Array
GPL2005 [Mapping50K_Xba240] Affymetrix Human Mapping 50K Xba240 SNP Array
Samples (4)
GSM437971 Blood_control_pool_HindIII
GSM437972 Blood_statin myopathy_pool_HindIII
GSM437973 Blood_control_pool_XbaI
Relations
BioProject PRJNA118677

Data table header descriptions
Rank Rank
Vendor ID Vendor ID
RS ID RS ID
Position Position
Chromosome Chromosome
Cytoband Cytoband
Case GTYPE SNP intensity for case
Control GTYPE SNP intensity for control
z-squared Z-score, the p-value of the z-squared test for estimate of association between any SNP in the DNA pools being compared

Data table
Rank Vendor ID RS ID Position Chromosome Cytoband Case Control z-squared
1 SNP_A-1670366 rs4143179 145205946 6 q24.2 0.819369 0.428755 3.10E-07
2 SNP_A-1743493 rs1074201 87815648 13 q31.2 0.683432 0.99 3.84E-07
3 SNP_A-1682608 rs2863759 91130488 10 q23.31 0.975434 0.669597 1.12E-06
4 SNP_A-1674239 rs9291159 3036730 4 p16.3 0.469645 0.117762 1.55E-06
5 SNP_A-1730599 rs1148417 105149862 12 q23.3 0.202376 0.565065 2.91E-06
6 SNP_A-1653338 rs6777583 107546384 3 q13.11 0.30963 0.676774 4.06E-06
7 SNP_A-1719522 rs631269 54417196 6 p12.1 0.405928 0.085362 5.05E-06
8 SNP_A-1660292 rs10432416 151211589 2 q23.3 0.960109 0.671139 6.70E-06
9 SNP_A-1668593 rs6496469 86536314 15 q25.3 0.633234 0.276527 7.55E-06
10 SNP_A-1709460 rs1565781 76045613 16 q23.1 0.257554 0.607199 1.06E-05
11 SNP_A-1683613 rs10485517 15051600 20 p12.1 0.85031 0.525926 1.50E-05
12 SNP_A-1684690 rs10491216 3267156 17 p13.3 0.62971 0.918892 2.96E-05
13 SNP_A-1727632 rs1454552 220895793 2 q35 0.469359 0.794527 3.15E-05
14 SNP_A-1719594 rs1852556 131811498 2 q21.1 0.192266 0.51307 3.36E-05
15 SNP_A-1673530 rs10521986 32021500 X p21.1 0.017003 0.261847 3.52E-05
16 SNP_A-1727361 rs3002309 212611255 1 q41 0.924641 0.646453 4.29E-05
17 SNP_A-1703052 rs1255832 162317282 4 q32.2 0.901982 0.613835 4.32E-05
18 SNP_A-1745735 rs10509703 97914430 10 q23.33 0.529098 0.209218 4.40E-05
19 SNP_A-1707995 rs10502887 43433881 18 q21.1 0.40663 0.731442 5.02E-05
20 SNP_A-1650766 rs10499047 107089821 6 q21 0.507492 0.817868 5.64E-05

Total number of rows: 102833

Table truncated, full table size 7440 Kbytes.




Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17574_RAW.tar 110.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
Processed data are available on Series record

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