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| Status |
Public on Apr 01, 2022 |
| Title |
Whole-genome mapping of ETV6-RUNX1 in pre-B lymphoblast models |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Genome binding/occupancy profiling of ETS Variant Transcription Factor 6- Runt Related Transcription Factor 1 fusion protein (ETV6-RUNX1) in REH cells by high throughput sequencing. ETV6-RUNX1 is expressed in pediatric t(12;21) ETV6-RUNX1 B cell precursor acute lymphoblastic leukemia.
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| Overall design |
ETV6-RUNX1 genome-wide distribution is determined using ChIP-seq. Cells used in this study are pre-B lymphoblast REH cells. ChIP samples and libraries were done by Sérandour A.A and Debaize L. High-throughput sequencing was conducted on a Genome HiSeq1500/2500. The input, REH RUNX1 Chip-Seq and histone marks are deposited in GEO GSE117684.
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| Contributor(s) |
Troadec MB, Debaize L |
| Citation(s) |
34535762 |
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| Submission date |
Jun 03, 2021 |
| Last update date |
Apr 02, 2022 |
| Contact name |
Gilles Salbert |
| Organization name |
University Rennes 1
|
| Department |
IGDR UMR6290
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| Street address |
263 Av. Gal. Leclerc
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| City |
Rennes |
| ZIP/Postal code |
35200 |
| Country |
France |
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| Platforms (2) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
| GPL18460 |
Illumina HiSeq 1500 (Homo sapiens) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA734856 |
| SRA |
SRP322432 |
