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Status |
Public on Feb 24, 2015 |
Title |
Study of the role of AMP-activated protein kinase (AMPK) in heart |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Transcriptional profiling of mouse ventricular tissue comparing WT control mice with mice invalidated (KO) for AMPK-alpha 2 gene. Goal was to identify new biological targets of AMPK in heart, through a global gene expression approach.
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Overall design |
Two-condition experiment, KO vs. Control WT mice. Biological replicates: 6 WT (AMPK alpha2 +/+) control mice, 6 KO (AMPK alpha2 -/-) mice.
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Contributor(s) |
Deloménie C, Garnier A |
Citation missing |
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Submission date |
Nov 02, 2009 |
Last update date |
Feb 24, 2015 |
Contact name |
Claudine DELOMENIE |
E-mail(s) |
[email protected]
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Phone |
33 1 46 83 57 85
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Organization name |
University Paris Sud 11
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Department |
Transcriptomique
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Lab |
Plate-forme Trans-Prot
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Street address |
5, rue Jean-Baptiste Clément
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City |
CHATENAY-MALABRY |
ZIP/Postal code |
92296 |
Country |
France |
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Platforms (1) |
GPL2872 |
Agilent-012694 Whole Mouse Genome G4122A (Feature Number version) |
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Samples (12)
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GSM469282 |
WT control AMPK alpha 2 +/+ Animal Replicate 1 |
GSM469283 |
WT control AMPK alpha 2 +/+ Animal Replicate 2 |
GSM469284 |
WT control AMPK alpha 2 +/+ Animal Replicate 3 |
GSM469285 |
WT control AMPK alpha 2 +/+ Animal Replicate 4 |
GSM469286 |
WT control AMPK alpha 2 +/+ Animal Replicate 5 |
GSM469287 |
WT control AMPK alpha 2 +/+ Animal Replicate 6 |
GSM469288 |
KO AMPK alpha 2 -/- Animal Replicate 1 |
GSM469289 |
KO AMPK alpha 2 -/- Animal Replicate 2 |
GSM469290 |
KO AMPK alpha 2 -/- Animal Replicate 3 |
GSM469291 |
KO AMPK alpha 2 -/- Animal Replicate 4 |
GSM469292 |
KO AMPK alpha 2 -/- Animal Replicate 5 |
GSM469293 |
KO AMPK alpha 2 -/- Animal Replicate 6 |
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Relations |
BioProject |
PRJNA121181 |