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Series GSE201600 Query DataSets for GSE201600
Status Public on Sep 28, 2022
Title Immunologic adapatations of high grade serous ovarian cancer patients to neoadjuvant carboplatin and paclitaxel therapy
Organism Homo sapiens
Experiment type Other
Summary 770 genes as well as pathways and deconvoluted immune cell types were determined pre- and post-neoadjuvant chemotherapy in a cohort of 31 stage III-IV high grade serous ovarian cancer (HGSOC) patients, and associations were made with the duration of their platinum-free interval
n/a
 
Overall design A total of 31 HGSOC patients were included in this retrospective study. Matched formalin-fixed, paraffin-embedded (FFPE) tumor tissues from treatment naive biopsies and interval debulking surgery following neoadjuvant chemotherapy were obtained from each patient, with associated clinical information, for a total of 62 samples. All patients received frontline carboplatin and paclitaxel although some patients received additional therapies. NanoString nCounter Human PanCancer IO360 panel was used to analyze isolated RNA for 770 genes associated with the tumor immune microenvironment.
 
Contributor(s) Ribeiro JR, James NE, Schorl C, Hanley LC
Citation(s) 36131935
Submission date Apr 26, 2022
Last update date Sep 29, 2022
Contact name Jennifer Renee Ribeiro
E-mail(s) [email protected]
Organization name Women and Infants Hospital of Rhode Island
Department Obstetrics and Gynecology
Street address 200 Chestnut St.
City Providence
State/province RI
ZIP/Postal code 02903
Country USA
 
Platforms (1)
GPL27956 NanoString Human nCounter PanCancer IO 360 Panel
Samples (62)
GSM6068308 Post patient 1 [Sample 1]
GSM6068309 Post patient 2 [Sample 2]
GSM6068310 Post patient 3 [Sample 3]
Relations
BioProject PRJNA832292

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE201600_Processed_Data.xlsx 502.7 Kb (ftp)(http) XLSX
GSE201600_RAW.tar 590.0 Kb (http)(custom) TAR (of RCC)
Processed data included within Sample table
Processed data are available on Series record

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