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| Status |
Public on Mar 01, 2010 |
| Title |
Effect of BMP4 and noggin on gene expression in murine R1 ES cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To confirm that the SMAD1/5- and SMAD4-associated genes are direct transcriptional regulators in mESCs in response to BMP, we treated undifferentiated R1 ES cells with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively for 4 h.
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| Overall design |
Undifferentiated R1 ES cells were treated for 4 h with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively. Untreated R1 ES cells served as the control.
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| Contributor(s) |
Fei T, Xia K, Li Z, Zhou B, Zhu S, Chen H, Zhang J, Chen Z, Xiao H, Han JJ, Chen Y |
| Citation(s) |
19926752 |
| |
| Submission date |
Feb 25, 2010 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Bing Zhou |
| E-mail(s) |
[email protected]
|
| Phone |
8610-64845797
|
| Fax |
8610-64845797
|
| URL |
http://hanlab.genetics.ac.cn
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| Organization name |
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
|
| Department |
Center for Molecular Systems Biology
|
| Lab |
Laboratory of Jing-Dong Jackie Han
|
| Street address |
Datun Road
|
| City |
Beijing |
| ZIP/Postal code |
100101 |
| Country |
China |
| |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA125141 |
