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| Status |
Public on Jul 26, 2022 |
| Title |
The role of core circadian component BMAL1 or CLOCK in human bone marrow mesenchymal stem cells osteogenic capacity |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To elucidate how the core circadian component BMAL1 and clock regulate the osteogenic capacity of human bone marrow MSCs, RNA-seq was performed to study the impact of diminishing core component BMAL1 or CLOCK in MSCs by lentiviruses.
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| Overall design |
Examination of the mRNA profiles in human bone marrow MSCs with diminishing BMAL1 or CLOCK during osteogenic differentiation
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| Contributor(s) |
Shen H, Xie Z, Yu W |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jul 21, 2022 |
| Last update date |
Aug 03, 2022 |
| Contact name |
Peitao Xu |
| E-mail(s) |
[email protected]
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| Organization name |
The Eighth Affiliated Hospital of Sun Yat-sen University
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| Street address |
No.3025, Shennan Middle Street
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| City |
Shenzhen |
| ZIP/Postal code |
518003 |
| Country |
China |
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| Platforms (1) |
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| Samples (9)
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| GSM6365614 |
MSC, Sh-BMAL1, rep2 |
| GSM6365615 |
MSC, Sh-CLOCK, rep2 |
| GSM6365616 |
MSC, Sh-NC, rep2 |
| GSM6365617 |
MSC, Sh-BMAL1, rep3 |
| GSM6365618 |
MSC, Sh-CLOCK, rep3 |
| GSM6365619 |
MSC, Sh-NC, rep3 |
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| This SubSeries is part of SuperSeries: |
| GSE210426 |
Bone formation in senile osteoporosisbone formation in senile osteoporosis |
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| Relations |
| BioProject |
PRJNA860821 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE208729_gene_expression.txt.gz |
1.5 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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