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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Nov 23, 2022 |
| Title |
BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Citation(s) |
36378541 |
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| Submission date |
Jul 29, 2022 |
| Last update date |
Nov 26, 2022 |
| Contact name |
Haobin Chen |
| E-mail(s) |
[email protected]
|
| Phone |
(845) 300-2498
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| Organization name |
National Institutes of Health
|
| Department |
Thoracic Surgery Branch
|
| Street address |
10 Center Drive, Room 3-5888
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| City |
Bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
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| Platforms (2) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
| GPL21290 |
Illumina HiSeq 3000 (Homo sapiens) |
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| Samples (71)
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| GSM6421390 |
H446 cells, Non-targeting gRNA, clone 3, DMSO, biol rep 1 |
| GSM6421391 |
H446 cells, Non-targeting gRNA, clone 3, DMSO, biol rep 2 |
| GSM6421392 |
H446 cells, Non-targeting gRNA, clone 3, DMSO, biol rep 3 |
| GSM6421393 |
H446 cells, Non-targeting gRNA, clone 10, DMSO, biol rep 1 |
| GSM6421394 |
H446 cells, Non-targeting gRNA, clone 10, DMSO, biol rep 2 |
| GSM6421395 |
H446 cells, Non-targeting gRNA, clone 10, DMSO, biol rep 3 |
| GSM6421396 |
H446 cells, Non-targeting gRNA, clone 13, DMSO, biol rep 1 |
| GSM6421397 |
H446 cells, Non-targeting gRNA, clone 13, DMSO, biol rep 2 |
| GSM6421398 |
H446 cells, Non-targeting gRNA, clone 13, DMSO, biol rep 3 |
| GSM6421399 |
H446 cells, Non-targeting gRNA, clone 3, JQ1, biol rep 1 |
| GSM6421400 |
H446 cells, Non-targeting gRNA, clone 3, JQ1, biol rep 2 |
| GSM6421401 |
H446 cells, Non-targeting gRNA, clone 3, JQ1, biol rep 3 |
| GSM6421402 |
H446 cells, Non-targeting gRNA, clone 10, JQ1, biol rep 1 |
| GSM6421403 |
H446 cells, Non-targeting gRNA, clone 10, JQ1, biol rep 2 |
| GSM6421404 |
H446 cells, Non-targeting gRNA, clone 10, JQ1, biol rep 3 |
| GSM6421405 |
H446 cells, Non-targeting gRNA, clone 13, JQ1, biol rep 1 |
| GSM6421406 |
H446 cells, Non-targeting gRNA, clone 13, JQ1, biol rep 2 |
| GSM6421407 |
H446 cells, Non-targeting gRNA, clone 13, JQ1, biol rep 3 |
| GSM6421408 |
H446 cells, NEUROD1 gRNA #297, clone 12, DMSO, biol rep 1 |
| GSM6421409 |
H446 cells, NEUROD1 gRNA #297, clone 12, DMSO, biol rep 2 |
| GSM6421410 |
H446 cells, NEUROD1 gRNA #297, clone 12, DMSO, biol rep 3 |
| GSM6421411 |
H446 cells, NEUROD1 gRNA #297, clone 15, DMSO, biol rep 1 |
| GSM6421412 |
H446 cells, NEUROD1 gRNA #297, clone 15, DMSO, biol rep 2 |
| GSM6421413 |
H446 cells, NEUROD1 gRNA #297, clone 15, DMSO, biol rep 3 |
| GSM6421414 |
H446 cells, NEUROD1 gRNA #297, clone 2-1, DMSO, biol rep 1 |
| GSM6421415 |
H446 cells, NEUROD1 gRNA #297, clone 2-1, DMSO, biol rep 2 |
| GSM6421416 |
H446 cells, NEUROD1 gRNA #297, clone 2-1, DMSO, biol rep 3 |
| GSM6421417 |
H446 cells, NEUROD1 gRNA #297, clone 12, JQ1, biol rep 1 |
| GSM6421418 |
H446 cells, NEUROD1 gRNA #297, clone 12, JQ1, biol rep 2 |
| GSM6421419 |
H446 cells, NEUROD1 gRNA #297, clone 12, JQ1, biol rep 3 |
| GSM6421420 |
H446 cells, NEUROD1 gRNA #297, clone 15, JQ1, biol rep 1 |
| GSM6421421 |
H446 cells, NEUROD1 gRNA #297, clone 15, JQ1, biol rep 2 |
| GSM6421422 |
H446 cells, NEUROD1 gRNA #297, clone 15, JQ1, biol rep 3 |
| GSM6421423 |
H446 cells, NEUROD1 gRNA #297, clone 2-1, JQ1, biol rep 1 |
| GSM6421424 |
H446 cells, NEUROD1 gRNA #297, clone 2-1, JQ1, biol rep 2 |
| GSM6421425 |
H446 cells, NEUROD1 gRNA #297, clone 2-1, JQ1, biol rep 3 |
| GSM6421441 |
COR-L279 cells, DMSO, 24hrs, biol rep 1 |
| GSM6421442 |
COR-L279 cells, DMSO, 24hrs, biol rep 2 |
| GSM6421443 |
COR-L279 cells, DMSO, 24hrs, biol rep 3 |
| GSM6421444 |
COR-L279 cells, 0.5µM JQ1, 24hrs, biol rep 1 |
| GSM6421445 |
COR-L279 cells, 0.5µM JQ1, 24hrs, biol rep 2 |
| GSM6421446 |
COR-L279 cells, 0.5µM JQ1, 24hrs, biol rep 3 |
| GSM6421447 |
COR-L279 cells, 1.5µM JQ1, 24hrs, biol rep 1 |
| GSM6421448 |
COR-L279 cells, 1.5µM JQ1, 24hrs, biol rep 2 |
| GSM6421449 |
COR-L279 cells, 1.5µM JQ1, 24hrs, biol rep 3 |
| GSM6421523 |
LX22_326R, vehicle, 5 days |
| GSM6421524 |
LX22_397L, vehicle, 5 days |
| GSM6421525 |
LX22_326L, vehicle, 5 days |
| GSM6421526 |
LX22_399L, vehicle, 5 days |
| GSM6421527 |
LX22_397R, vehicle, 5 days |
| GSM6421528 |
LX22_399R, vehicle, 5 days |
| GSM6421529 |
LX22_395R, NHWD-870, 5 days |
| GSM6421530 |
LX22_425R, NHWD-870, 5 days |
| GSM6421531 |
LX22_395L, NHWD-870, 5 days |
| GSM6421532 |
LX22_392R, NHWD-870, 5 days |
| GSM6421533 |
LX22_392L, NHWD-870, 5 days |
| GSM6421534 |
LX22_425L, NHWD-870, 5 days |
| GSM6421550 |
H446 NTgRNA, Input |
| GSM6421551 |
H446 ND1-KO, Input |
| GSM6421552 |
H446 NTgRNA, H3K27Ac, Abcam |
| GSM6421553 |
H446 ND1-KO, H3K27Ac, Abcam |
| GSM6421554 |
H446 NTgRNA, NEUROD1, CST |
| GSM6421555 |
H446 ND1-KO, NEUROD1, CST |
| GSM6421556 |
H446 NTgRNA, Pol II, EMD/Millipore |
| GSM6421557 |
H446 ND1-KO, Pol II, EMD/Millipore |
| GSM6421558 |
H446 NTgRNA, BRD2, CST |
| GSM6421559 |
H446 ND1-KO, BRD2, CST |
| GSM6421560 |
H446 NTgRNA, BRD3, Bethyl |
| GSM6421561 |
H446 ND1-KO, BRD3, Bethyl |
| GSM6421562 |
H446 NTgRNA, BRD4, Bethyl |
| GSM6421563 |
H446 ND1-KO, BRD4, Bethyl |
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| This SuperSeries is composed of the following SubSeries:
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| GSE210101 |
BET inhibitors target the SCLC-N subtype of small-cell lung cancer by blocking NEUROD1 transactivation |
| GSE210104 |
BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation |
| GSE210110 |
BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation |
| GSE210113 |
BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation |
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| Relations |
| BioProject |
PRJNA863665 |
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