|
| Status |
Public on Aug 25, 2023 |
| Title |
Human blastoid |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Based on our previous works, we established an optimized protocol that enables the generation of blastocyst-like structures from human pluripotent stem cells.
|
| |
|
| Overall design |
To model human pre-/peri-implantation development, we reported a optimized protocol to generate blastocyst-like structures from human pluripotent stem cells (hPSCs) in vitro, which resemble blastocysts in morphology and cell-lineage allocation. Human blastoids provide an accessible, scalable, versatile, and manipulable in vitro model to study the early stages of human development and implantation.
|
| |
|
| Contributor(s) |
Hon G, Duan J |
| Citation(s) |
37683605 |
| |
| Submission date |
Aug 10, 2022 |
| Last update date |
Nov 25, 2023 |
| Contact name |
Gary Hon |
| Organization name |
UT Southwestern
|
| Department |
Department of Obstetrics and Gynecology
|
| Lab |
Hon Lab
|
| Street address |
5323 Harry Hines Blvd.
|
| City |
Dallas |
| ZIP/Postal code |
75390 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (1) |
|
| This SubSeries is part of SuperSeries: |
|
| Relations |
| BioProject |
PRJNA868377 |
