|
| Status |
Public on Sep 22, 2022 |
| Title |
CCL17 promotes colitis-associated tumorigenesis dependent on the microbiota |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
• CCL17 expression is increased in colitis-associated colon tumors
• Single-housed CCL17-deficient mice develop fewer tumors dependent on the microbiota
• Reduced tumor numbers coincide with increased apoptosis during tumor initiation
|
| |
|
| Overall design |
Sorted cells from tumors from CCL17 ko mice cohoused with control mice or CCL17 ko mice separately housed after AOM DSS treatment
|
| |
|
| Contributor(s) |
Metzger R, Öllinger R |
| Citation(s) |
36426975 |
| |
| Submission date |
Sep 20, 2022 |
| Last update date |
Jun 30, 2023 |
| Contact name |
Rebecca Metzger |
| E-mail(s) |
[email protected]
|
| Organization name |
LMU
|
| Street address |
Großhaderner Strasse 9
|
| City |
Planegg |
| ZIP/Postal code |
82152 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (48)
|
|
| Relations |
| BioProject |
PRJNA882384 |
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