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| Status |
Public on Feb 15, 2023 |
| Title |
Integrated whole-exome and transcriptome sequencing indicated dysregulation of cholesterol metabolism in eyelid sebaceous gland carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by high throughput sequencing
Expression profiling by high throughput sequencing
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| Summary |
To identify the molecular background of eyelid sebaceous gland carcinomas (SCs), the integrated whole-exome sequencing and transcriptome sequencing for five eyelid SCs were conducted in this study.
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| Overall design |
The genetic alterations were studied by whole-exome sequencing, and the mRNA expression was studied using Oxford Nanopore Technologies (ONT) in five paired fresh eyelid SC tissues and adjacent normal tissues.
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| Contributor(s) |
Wang Y, Li J, Hao P, Li X |
| Citation(s) |
36735267 |
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| Submission date |
Dec 01, 2022 |
| Last update date |
Feb 15, 2023 |
| Contact name |
Yuchuan Wang |
| E-mail(s) |
[email protected]
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| Organization name |
Tianjin Eye hospital
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| Street address |
Gansu Road
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| City |
Tianjin |
| ZIP/Postal code |
300020 |
| Country |
China |
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| Platforms (2) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
| GPL26167 |
PromethION (Homo sapiens) |
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| Samples (20)
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| GSM6777830 |
S1-N, adjacent normal tissues (WES) |
| GSM6777831 |
S1-T, eyelid sebaceous gland carcinoma tissue (WES) |
| GSM6777832 |
S2-N, adjacent normal tissues (WES) |
| GSM6777833 |
S2-T, eyelid sebaceous gland carcinoma tissue (WES) |
| GSM6777834 |
S3-N, adjacent normal tissues (WES) |
| GSM6777835 |
S3-T, eyelid sebaceous gland carcinoma tissue (WES) |
| GSM6777836 |
S4-N, adjacent normal tissues (WES) |
| GSM6777837 |
S4-T, eyelid sebaceous gland carcinoma tissue (WES) |
| GSM6777838 |
S5-N, adjacent normal tissues (WES) |
| GSM6777839 |
S5-T, eyelid sebaceous gland carcinoma tissue (WES) |
| GSM6777840 |
S1-N, adjacent normal tissues (RNA-seq) |
| GSM6777841 |
S1-T, eyelid sebaceous gland carcinoma tissue (RNA-seq) |
| GSM6777842 |
S2-N, adjacent normal tissues (RNA-seq) |
| GSM6777843 |
S2-T, eyelid sebaceous gland carcinoma tissue (RNA-seq) |
| GSM6777844 |
S3-N, adjacent normal tissues (RNA-seq) |
| GSM6777845 |
S3-T, eyelid sebaceous gland carcinoma tissue (RNA-seq) |
| GSM6777846 |
S4-N, adjacent normal tissues (RNA-seq) |
| GSM6777847 |
S4-T, eyelid sebaceous gland carcinoma tissue (RNA-seq) |
| GSM6777848 |
S5-N, adjacent normal tissues (RNA-seq) |
| GSM6777849 |
S5-T, eyelid sebaceous gland carcinoma tissue (RNA-seq) |
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| Relations |
| BioProject |
PRJNA907396 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE219205_All_gene_expression.list.txt.gz |
829.9 Kb |
(ftp)(http) |
TXT |
| GSE219205_S1-T.vs.S1-N.SNP.hg19_multianno.GO_KEGG.txt.gz |
119.7 Kb |
(ftp)(http) |
TXT |
| GSE219205_S1-T.vs.S1-N.indel.hg19_multianno.GO_KEGG.txt.gz |
154.1 Kb |
(ftp)(http) |
TXT |
| GSE219205_S2-T.vs.S2-N.SNP.hg19_multianno.GO_KEGG.txt.gz |
70.4 Kb |
(ftp)(http) |
TXT |
| GSE219205_S2-T.vs.S2-N.indel.hg19_multianno.GO_KEGG.txt.gz |
106.5 Kb |
(ftp)(http) |
TXT |
| GSE219205_S3-T.vs.S3-N.SNP.hg19_multianno.GO_KEGG.txt.gz |
73.6 Kb |
(ftp)(http) |
TXT |
| GSE219205_S3-T.vs.S3-N.indel.hg19_multianno.GO_KEGG.txt.gz |
89.6 Kb |
(ftp)(http) |
TXT |
| GSE219205_S4-T.vs.S4-N.SNP.hg19_multianno.GO_KEGG.txt.gz |
73.0 Kb |
(ftp)(http) |
TXT |
| GSE219205_S4-T.vs.S4-N.indel.hg19_multianno.GO_KEGG.txt.gz |
98.6 Kb |
(ftp)(http) |
TXT |
| GSE219205_S5-T.vs.S5-N.SNP.hg19_multianno.GO_KEGG.txt.gz |
72.1 Kb |
(ftp)(http) |
TXT |
| GSE219205_S5-T.vs.S5-N.indel.hg19_multianno.GO_KEGG.txt.gz |
91.9 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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