|
| Status |
Public on May 12, 2023 |
| Title |
A novel Modulator of Ring Stage Translation (MRST) gene alters artemisinin sensitivity in Plasmodium falciparum |
| Organism |
Plasmodium falciparum |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNAseq data profiling the artemisinin-sensitive P. falciparum piggyBac mutant of the PF3D7_1136600 gene (conserved Plasmodium gene, unknown function)
|
| |
|
| Overall design |
Each run-folder contains paired-end fastq data for two complete bioreps of the two parasite lines (NF54 wild-type control; artemisinin-sensitive mutant referred to in sample-names as PB52) collected after 3 rounds of sortibol synchronization under normal asexual growth conditions. Parasites were at early ring stage (T6), mid ring stage (T12), early trophozoite stage (T24), late trophozoite stage (T36), or schizont stage (T48) as verified by Giemsa-stained microscopy. Each sample was run on an Illumina Nextseq
|
| |
|
| Contributor(s) |
Simmons C, Gibbons J, Wang C, Pires CV, Zhang M, Oberstaller J, Casandra D, Seyfang A, Otto TD, Adams JH |
| Citation(s) |
37219373 |
| |
| Submission date |
Jan 23, 2023 |
| Last update date |
Sep 14, 2023 |
| Contact name |
Caroline Simmons |
| E-mail(s) |
[email protected]
|
| Organization name |
University of South Florida
|
| Street address |
3720 E Spectrum Blvd
|
| City |
Tampa |
| State/province |
Florida |
| ZIP/Postal code |
33620 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL26920 |
NextSeq 550 (Plasmodium falciparum) |
|
| Samples (20)
|
|
| Relations |
| BioProject |
PRJNA926593 |
Less...
More...