|
| Status |
Public on Mar 04, 2024 |
| Title |
COVID-19 vaccination is associated with attenuation of inflammatory responses during breakthrough disease [long-read RNA-Seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
A subset of individualsenrolledina randomised controlled trial ofChAdOx1 nCoV-19 and received either ChAdOx1 COVID-19 or control MenACWY vaccine whoexperienced COVID-19-associated symptoms were evaluated using multi-omictechnologies. Participants were selected to represent symptomatic individuals with and without COVID-19 as determined by a nucleic acid amplification test (NAAT).
|
| |
|
| Overall design |
Blood samples taken on theday of vaccination were compared with samples taken at onset of COVID-19 associated symptoms.Long-read Nanopore PCR-cDNA sequencing technology was utilised.
|
| |
|
| Contributor(s) |
Chelysheva I, Drury R, O'Connor D, Camara S |
| Citation(s) |
38649734 |
| |
| Submission date |
Apr 03, 2023 |
| Last update date |
May 17, 2024 |
| Contact name |
Irina Chelysheva |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Oxford
|
| Department |
NDM
|
| Lab |
Centre for Human Genetics
|
| Street address |
Roosevelt Dr
|
| City |
Oxford |
| ZIP/Postal code |
OX3 7BN |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
|
| Samples (39)
|
|
| This SubSeries is part of SuperSeries: |
| GSE228842 |
COVID-19 vaccination is associated with attenuation of inflammatory responses during breakthrough disease |
|
| Relations |
| BioProject |
PRJNA951717 |
Less...
More...