|
| Status |
Public on Apr 11, 2023 |
| Title |
Multivalent vaccines demonstrate immunogenicity and protect against Coxiella burnetii aerosol challenge |
| Platform organism |
Coxiella burnetii |
| Sample organism |
Mus musculus |
| Experiment type |
Protein profiling by protein array
|
| Summary |
C57BL/6 mice were immunized with Coxiella burnetii vaccine Q-VAX (Seqirus) and monitored for up to 83 days post immunization. Two different routes of immunization were observed - subcutaneous and intramuscular. Subcutaneously immunized animals were boosted on day 67.
|
| |
|
| Overall design |
This study follows mice immunized with Q-VAX over the course of 83 days. Plasma from immunized animals were compared to naïve animals from day 0. There were 5 replicates for each route of immunization.
|
| |
|
| Contributor(s) |
Jan S, Fratzke AP, Felgner J, Hernandez-Davies JE, Liang L, Nakajima R, Jasinskas A, Supnet M, Jain A, Felgner PL, Davies DH, Gregory AE |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 10, 2023 |
| Last update date |
Apr 11, 2023 |
| Contact name |
Sharon Jan |
| E-mail(s) |
[email protected]
|
| Organization name |
UC Irvine
|
| Department |
Physiology & Biophysics
|
| Street address |
812 Medical Plaza Dr Rm 387 Med Surge II
|
| City |
Irvine |
| State/province |
CA |
| ZIP/Postal code |
92697 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL33327 |
Coxiella burnetii Antigen Microarray 12 |
|
| Samples (40)
|
|
| Relations |
| BioProject |
PRJNA953973 |
Less...
More...