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| Status |
Public on May 31, 2023 |
| Title |
Effect of Rheb depletion of Rheb and Ribo-HA knock-in on gene expression of neurons |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To examine the effect of neuronal Rheb on brain myelination, we generated a conditional neuronal Rheb knockout mouse line.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for Control and Rheb cKO mice.
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| Web link |
https://pubmed.ncbi.nlm.nih.gov/37463107/
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| Contributor(s) |
Tang P, Florea LD, Antonescu C |
| Citation(s) |
37463107 |
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| Submission date |
Apr 22, 2023 |
| Last update date |
Aug 31, 2023 |
| Contact name |
Alexander Platero |
| E-mail(s) |
[email protected]
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| Organization name |
Johns Hopkins SOM
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| Department |
Neuroscience
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| Lab |
Worley
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| Street address |
725 N. Wolfe st
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| City |
Baltimore |
| State/province |
MD |
| ZIP/Postal code |
21205 |
| Country |
USA |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (6)
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| GSM7220305 |
Rheb floxp/floxp; Ribo-HA k/+; Syn-Cre, P25, 1 |
| GSM7220306 |
Rheb floxp/floxp; Ribo-HA k/+; Syn-Cre, P25, 2 |
| GSM7220307 |
Rheb floxp/floxp; Ribo-HA k/+; Syn-Cre, P25, 3 |
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| Relations |
| BioProject |
PRJNA960656 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE230354_Rheb_gene_exp.diff.OK._processed.xlsx |
1.6 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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