|
| Status |
Public on Apr 13, 2024 |
| Title |
DUSP6 inhibition overcomes Neuregulin/HER3-driven therapy resistance in HER2+ breast cancer [MDA] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate transcriptomic changes regulated by DUSP6 in a HER2+ breast cancer cell line
We performed gene expression profiling analysis using data obtained from RNA-seq of SCR vs DUSP6 KD MDA-MB-453 cells
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| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for SCR controls vs. DUSP6 KD model
|
| |
|
| Contributor(s) |
Momeny M, Laajala T, Westermarck J |
| Citation(s) |
38886591 |
| |
| Submission date |
May 02, 2023 |
| Last update date |
Jul 13, 2024 |
| Contact name |
Teemu Daniel Laajala |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Turku
|
| Department |
Department of Mathematics and Statistics
|
| Street address |
Turun yliopisto
|
| City |
Turku |
| ZIP/Postal code |
20014 |
| Country |
Finland |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (6)
|
| GSM7287665 |
MDA-MB-453, Scrambled, Sample ID 1, rep1 |
| GSM7287666 |
MDA-MB-453, Scrambled, Sample ID 2, rep2 |
| GSM7287667 |
MDA-MB-453, Scrambled, Sample ID 4, rep3 |
| GSM7287668 |
MDA-MB-453, DUSP6 Knockdown, Sample ID 3, rep1 |
| GSM7287669 |
MDA-MB-453, DUSP6 Knockdown, Sample ID 5, rep2 |
| GSM7287670 |
MDA-MB-453, DUSP6 Knockdown, Sample ID 6, rep3 |
|
| This SubSeries is part of SuperSeries: |
| GSE231526 |
DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer |
|
| Relations |
| BioProject |
PRJNA966202 |
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