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| Status |
Public on Aug 16, 2023 |
| Title |
RNA-seq analysis in RPMI-8402 cells after knockout of MYCN |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA-seq analysis was performed in a RPMI-8402 T-ALL cell stably expressing Cas9 after knockout of MYCN
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| Overall design |
RPMI-8402 cells stably expressing Cas9 were treated with either DMSO (Control) or Doxycline to induce expression of sgRNAs against MYCN for 72 hours. Cells were then harvested and total RNA were extracted for library preparation and RNA-Seq analysis
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| Contributor(s) |
Tan SH, Tan TK, Sanda T |
| Citation(s) |
37591943 |
| |
| Submission date |
May 08, 2023 |
| Last update date |
Nov 20, 2023 |
| Contact name |
Tze King Tan |
| Organization name |
National University of Singapore
|
| Department |
Cancer Science Institute
|
| Lab |
Takaomi Sanda Lab
|
| Street address |
14 Medical Drive
|
| City |
Singapore |
| ZIP/Postal code |
117599 |
| Country |
Singapore |
| |
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| Platforms (1) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE231965 |
TAL1 hijacks MYCN enhancer that induces MYCN expression and dependence on mevalonate pathway in T-cell acute lymphoblastic leukemia |
|
| Relations |
| BioProject |
PRJNA970308 |
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