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| Status |
Public on Jun 26, 2024 |
| Title |
Unraveling the Role of Srsf1 in Brown Adipose Tissue Thermogenic Function through Single-Nucleus RNA Sequencing. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Single-nucleus RNA sequencing reveals that Srsf1 absence alters the cell type composition and differentiation trajectories of BAT.
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| Overall design |
Interscapular brown adipose tissue was harvested from 8-week-old control and adipose tissue-specific Srsf1-knockout mice for experiment. In order to obtain single-cell suspension, fresh tissue samples were cut and lysed in nucleus lysis solution. The nuclei obtained were subsequently used for sequencing.
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| |
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| Contributor(s) |
Yuan N, Feng Y |
| Citation(s) |
38569495 |
| |
| Submission date |
Jul 21, 2023 |
| Last update date |
Jun 27, 2024 |
| Contact name |
Yuan Ning Yang |
| E-mail(s) |
[email protected]
|
| Phone |
18562311335
|
| Organization name |
Shanghai Institute of Nutrition and Health,CAS
|
| Lab |
CAS Key Laboratory of Nutrition Metabolism and Food Safety
|
| Street address |
320 Yueyang Road
|
| City |
Shanghai |
| State/province |
Shanghai |
| ZIP/Postal code |
200031 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA997366 |
