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| Status |
Public on Dec 31, 2023 |
| Title |
MeDIP-seq profiles of mouse ApcDHep hepatocytes at day 6 vs wt hepatocytes |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
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| Summary |
We analyzed the level of DNA methylation by MeDIPseq in hepatocytes isolated by collagenase perfusion from Apclox/loxlivers, six days after injection of 2mg tamoxifen vs wt hepatocytes. Our aims was to study the impact of the beta-catenin on DNA methylation during the early steps of liver tumorigenesis
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| Overall design |
DNA isolated from mouse ApcDHep hepatocytes at day 6 vs wt hepatocytes by Phenol/chloroform technique was immunoprecipitated by anti-5-methylcytosine (Active motif)
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| Contributor(s) |
Gougelet A, Colnot S |
| Citation(s) |
31194980 |
| |
| Submission date |
Aug 01, 2023 |
| Last update date |
Mar 31, 2024 |
| Contact name |
Angelique Gougelet |
| E-mail(s) |
[email protected]
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| Organization name |
INSERM U1138
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| Street address |
15 rue de l'école de médecine
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| City |
Paris |
| ZIP/Postal code |
75006 |
| Country |
France |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA1000949 |
