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| Status |
Public on Sep 23, 2010 |
| Title |
CpG B and R848 induced gene expression in IRAK2 wildtype and deficient mouse macrophages |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Compared to wildtype macrophages, IRAK2 deficient macrophages show higher induced gene expression in responsse to CpG B, but not R848
Manuscipt title: The dual function of IRAK2 in TLR9-mediated interfereon and proinflammatory cytokine production
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| Overall design |
Bone marrow derived macrophages from wildtype and IRAK2 knockout mouse were stimulated with CpG B or R848 for 2 hours, or untreated.
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| Contributor(s) |
Wan Y, Li X, Faber PW |
| Citation(s) |
21270393 |
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| Submission date |
Sep 22, 2010 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Youzhong Wan |
| Organization name |
Cleveland Clinic Foundation
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| Department |
Immunology
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| Lab |
Xiaoxia Li
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| Street address |
9500 Euclid Avenue, NE20
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| City |
Cleveland |
| State/province |
OH |
| ZIP/Postal code |
44195 |
| Country |
USA |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (6)
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| GSM596839 |
IRAK2 deficient macrophages, untreated |
| GSM596840 |
IRAK2 deficient macrophages, R848 2h |
| GSM596841 |
IRAK2 deficient macrophages, CpG B 2h |
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| Relations |
| BioProject |
PRJNA132993 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE24264_RAW.tar |
3.1 Mb |
(http)(custom) |
TAR |
| GSE24264_non-normalized.txt.gz |
707.0 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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