|
| Status |
Public on Jan 25, 2012 |
| Title |
Genome-wide binding profiles of the B-Myb-MuvB complex in HeLa cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
To identify genomic regions bound by B-Myb and LIN9 (a subunit of the MuvB complex), we performed ChIP-Sequencing (ChIP-Seq) using chromatin from proliferating HeLa cells in which we can detect a robust association between B-Myb and subunits of the MuvB complex. This analysis allowed us identify late cell cycle or G2/M expressed genes as specific targets of the B-Myb-MuvB complex.
|
| |
|
| Overall design |
Examination of B-Myb and LIN9 binding in asynchronously growing HeLa cells
|
| |
|
| Contributor(s) |
Sadasivam S, DeCaprio JA |
| Citation(s) |
22391450 |
| |
| Submission date |
Feb 02, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Subhashini Sadasivam |
| E-mail(s) |
[email protected]
|
| Organization name |
Dana Farber Cancer Insitute
|
| Department |
Medical Oncology
|
| Lab |
Laboratory of James DeCaprio, Mayer 444
|
| Street address |
450 Brookline Avenue
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9115 |
Illumina Genome Analyzer II (Homo sapiens) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE27031 |
The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression |
|
| Relations |
| SRA |
SRP005609 |
| BioProject |
PRJNA142047 |
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