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Series GSE270959 Query DataSets for GSE270959
Status Public on Jul 02, 2024
Title Identification of targets for the transcription factor EFL-3 in the C. elegans epidermis
Organism Caenorhabditis elegans
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary In this study we employ NanoDam to identify targets within the epidermis for the transcription factor EFL-3 that we identified as a key epidermal development regulator.
 
Overall design Identification of EFL-3 genome-wide binding by epidermis-specific expression of GFP-nanobody:Dam fusion combined with EFL-3:GFP knock-in in C. elegans. Two different configurations of the GFP-nanobody:dam fusions are included (C-terminal and N-terminal fusions). Samples containing the GFP-nanobody:dam fusion only constitute control samples.
 
Contributor(s) Ferrando-Marco M, Barkoulas M
Citation missing Has this study been published? Please login to update or notify GEO.
Submission date Jun 27, 2024
Last update date Jul 02, 2024
Contact name Michalis Barkoulas
E-mail(s) [email protected]
Organization name Imperial College London
Department Life Sciences
Street address Imperial College Road
City London
ZIP/Postal code SW7 2AZ
Country United Kingdom
 
Platforms (1)
GPL22765 Illumina HiSeq 4000 (Caenorhabditis elegans)
Samples (8)
GSM8366285 EFL-3_NanoDam_N-t_dam-only_Rep1
GSM8366286 EFL-3_NanoDam_N-t_dam-only_Rep2
GSM8366287 EFL-3_NanoDam_C-t_dam-only_Rep1
Relations
BioProject PRJNA1129117

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE270959_C-tGFP-vs-Dam.gatc.chr.averagedQN-FDR0.05.peaks.valued.bed.gz 14.0 Kb (ftp)(http) BED
GSE270959_C-tGFP-vs-Dam.gatc.chr.averagedQN.bedgraph.gz 2.9 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP5-vs-Dam1.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP5-vs-Dam2.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP6-vs-Dam1.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP6-vs-Dam2.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP7-vs-Dam3.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP7-vs-Dam4.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP8-vs-Dam3.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_GFP8-vs-Dam4.gatc.bedgraph.gz 3.7 Mb (ftp)(http) BEDGRAPH
GSE270959_N-tGFP-vs-Dam.gatc.chr.averagedQN-FDR0.05.peaks.valued.bed.gz 12.9 Kb (ftp)(http) BED
GSE270959_N-tGFP-vs-Dam.gatc.chr.averagedQN.bedgraph.gz 2.9 Mb (ftp)(http) BEDGRAPH
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Raw data are available in SRA

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