|
| Status |
Public on Nov 20, 2024 |
| Title |
Sphingosine kinase 2 (SphK2) knockout alters metabolic gene expression in an early MASH mouse model |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
To determine the effect of SphK2 KO on liver metabolic-associated gene expression in an early MASH mouse model
To determine the effect of WDSW on liver metabolic-associated gene expression in an early MASH mouse model
|
| |
|
| Overall design |
Assessed two independent variables (diet, genotype) on on gene expression related to inflammation and the immune response in a MASH mouse model
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| |
|
| Contributor(s) |
Jackson K, Zhao D, Zhou H |
| Citation |
https://doi.org/10.1097/HC9.0000000000000570
|
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| F31 DK135372 |
The role of sphingosine kinase 2 in mitochondrial dysfunction and NAFLD |
VIRGINIA COMMONWEALTH UNIVERSITY |
Kaitlyn Georgene Jackson |
| I01 BX005730 |
Bile Acids and Sphingosine 1-Phosphate in Non-Alcoholic Steatohepatitis (NASH) |
VA VET ADMIN HOSPITAL |
Huiping Rose Zhou |
|
| |
| Submission date |
Oct 23, 2024 |
| Last update date |
Nov 21, 2024 |
| Contact name |
Kaitlyn G Jackson |
| E-mail(s) |
[email protected], [email protected]
|
| Organization name |
VCU
|
| Department |
Immunology
|
| Lab |
Zhou
|
| Street address |
7414 Seminary Ave
|
| City |
Richmond |
| State/province |
Virginia |
| ZIP/Postal code |
23227 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL35014 |
NanoString nCounter Metabolic Panel [NS_Mm_Metabolism] |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA1176455 |
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