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| Status |
Public on Dec 01, 2011 |
| Title |
Analysis of p53 target genes in melanoma part 1 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Although mutations in p53 are infrequent in human melanoma, its function is abnormal. In this study, whole genome bead arrays were used to examine the expression of p53 target genes in extracts from 82 metastatic melanoma samples, compared to extracts derived from diploid human melanocytes, to provide a global assessment of aberrant p53 function.
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| Overall design |
Total RNA extracted from 82 tumour samples and 8 melanocyte cell lines was analysed. Metastatic melanomas were compared to melanocyte cell lines.
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| Contributor(s) |
Avery-Kiejda KA, Bowden NA, Kairupan C, Croft AJ, Ashton KA, Scurr LL, Talseth-Palmer BA, Rizos H, Zhang XD, Scott RJ, Hersey P |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 17, 2011 |
| Last update date |
Jan 18, 2013 |
| Contact name |
Kelly Kiejda |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Newcastle
|
| Street address |
HMRI
|
| City |
New Lambton Heights |
| State/province |
NSW |
| ZIP/Postal code |
2305 |
| Country |
Australia |
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| Platforms (1) |
| GPL6104 |
Illumina humanRef-8 v2.0 expression beadchip |
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| Samples (90)
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| This SubSeries is part of SuperSeries: |
| GSE29377 |
Analysis of p53 target genes in melanoma |
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| Relations |
| BioProject |
PRJNA143001 |
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