|
| Status |
Public on Feb 16, 2012 |
| Title |
Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of BMP-2 induced gene expression of C2C12 cells treated with the endocytosis inhibitor dynasore to identify gene expression profiles which are sensitive to endocytosis inhibition.
Our data highlight the importance of endocytosis for transmission of an extracellular BMP-2 signal into the nucleus to activate a transcriptional gene network
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| |
|
| Overall design |
Total RNA obtained from C2C12 cells stimulated with BMP-2 together with the endocytosis inhibitor dynasore or DMSO as control compared to unstimulated cells treated with dynasore or DMSO alone.
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| |
|
| Contributor(s) |
Heining E, Bhushan R, Knaus P |
| Citation(s) |
21998639 |
| |
| Submission date |
May 18, 2011 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Raghu Bhushan |
| E-mail(s) |
[email protected]
|
| Phone |
00493083852945
|
| Fax |
00493083852936
|
| Organization name |
Freie Universität
|
| Department |
Institut für Chemie und Biochemie
|
| Lab |
Knaus lab
|
| Street address |
Thielallee 63
|
| City |
Berlin |
| State/province |
Berlin |
| ZIP/Postal code |
14195 |
| Country |
Germany |
| |
|
| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
| Samples (8)
|
|
| Relations |
| BioProject |
PRJNA140215 |
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