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GEO help: Mouse over screen elements for information. |
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Status |
Public on Nov 01, 2011 |
Title |
SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
Purpose of experiment was to perform transcriptomic analysis on C57Bl/6 mice infected with different doses of SARS CoV MA15 at 4 different days post infection.
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Overall design |
Twenty-week-old C57BL/6 mice were infected by intranasal instillation of 10^2, 10^3, 10^4 or 10^5 PFU of SARS CoV MA15 in 50 µl of PBS or mock-infected with PBS alone. At days 1, 2, 4 and 7 days post-infection, lungs were harvested and total RNA was isolated and subjected to microarray analysis. The experimental design was for 4- 5 mice/time point/dose and 3 time-matched mocks. The NIAID Systems Virology Center
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Contributor(s) |
Gralinski L, Bankhead A, Chang J, Baric R, Katze M, McWeeney S |
Citation(s) |
26015500, 30301856 |
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Submission date |
Oct 26, 2011 |
Last update date |
Oct 17, 2018 |
Contact name |
Michael Katze |
E-mail(s) |
[email protected]
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Organization name |
University of Washington
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Department |
Microbiology
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Lab |
Michael G. Katze, Ph.D
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Street address |
Rosen Building 960 Republican St.
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City |
Seattle |
State/province |
WA |
ZIP/Postal code |
98109-4325 |
Country |
USA |
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Platforms (1) |
GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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Samples (92)
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Relations |
BioProject |
PRJNA149057 |
Supplementary file |
Size |
Download |
File type/resource |
GSE33266_RAW.tar |
842.0 Mb |
(http)(custom) |
TAR (of TXT) |
Processed data included within Sample table |
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