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Status |
Public on Nov 07, 2012 |
Title |
Hepatic transcriptome in wild-type and LXR-deficient mice |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
LXR is a transcription factor. Two isoforms exist in mice (alpha and beta). They are both expressed in the liver. We examined the role of LXR by obtaining gene expression profiles from the livers of wild-type and LXR-/- mice from the same genetic background.
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Overall design |
Liver gene expression was measured from male mice (5 mice/group) of genotypes wild-type and LXR-/- on a mixed Sv129/C57Bl6J background (Repa et al. , 2000, Science, 289(5484):1524-9; Cummins et al., 2006, J Clin Invest,116(7):1902-12) fed for 7 weeks a normal diet (ND) or a Western diet (WD).
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Contributor(s) |
Ducheix S, Podechard N, Polizzi A, Pommier A, Lobaccaro J, Martin PG, Guillou H |
Citation(s) |
23063693 |
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Submission date |
May 21, 2012 |
Last update date |
Jan 12, 2017 |
Contact name |
Pascal GP Martin |
E-mail(s) |
[email protected]
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Organization name |
INRAE
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Department |
UMR1332 BFP
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Lab |
FDFE
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Street address |
71 avenue Edouard Bourlaux
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City |
Villenave d'Ornon |
ZIP/Postal code |
33140 |
Country |
France |
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Platforms (1) |
GPL7202 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version) |
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Samples (20)
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Relations |
BioProject |
PRJNA167195 |