|
| Status |
Public on Mar 03, 2006 |
| Title |
Profiling of ER+ BrC cells with and without estradiol in both cell cultures and xenografts |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We generated DNA microarray based gene expression profiles from three estrogen receptor a (ERa) positive breast cancer cell lines stimulated by 17ß-estradiol (E2) in vitro over a time course, as well as from MCF-7 cells grown as xenografts in ovariectomized athymic nude mice with E2 supplementation and after its withdrawal.
Keywords: Cell line and xenograft comparisons
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| |
|
| Overall design |
8 MCF-7 xenograft profiles (4 with E2,4 without E2), 14 T47D profiles (with E2 treatment in culture from 0 to 24 hr), 10 BT-474 profiles (with E2 treatment from 0 to 24 hr), 12 MCf-7 profiles (with E2 treatment from 0 to 24 hr)
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| |
|
| Contributor(s) |
Creighton C, Rae J, Lippman M |
| Citation(s) |
16606439 |
| |
| Submission date |
Dec 14, 2005 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Chad Creighton |
| E-mail(s) |
[email protected]
|
| Organization name |
Baylor College of Medicine
|
| Department |
Biostatistics, Ducan Cancer Center
|
| Street address |
One Baylor Plaza, Mail Stop: BCM305
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (47)
|
|
| Relations |
| BioProject |
PRJNA94051 |
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