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| Status |
Public on Dec 05, 2012 |
| Title |
Gene Expression Profiling In Murine Retina Neovascularization Models |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
In order to find out the vital genes during retinal neovascularization (RNV), we set up OIR (oxygen-induced retinopathy; induced with 75%±2% oxygen) and wild-type C57BL/6J murine models. We observed the retinal vascular growth process daily both in OIR and wild-type mice through retinal flat-mount, and isolated total retinal RNA at different time points (P8, P9, P12, P13, P30) both in OIR and wild-type mice for gene expression analysis.
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| Overall design |
At least three different retinae were accessed at each time point for observing the retinal vascular growth process. Ten neural retinae from five mice were harvested and pooled into one sample for gene expression analysis. Three biological replicates were used for each time point. Dye-swaps were performed.
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| Contributor(s) |
Yang X, Dong X, Jia C, Wang Y |
| Citation(s) |
23592914 |
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| Submission date |
Jun 15, 2012 |
| Last update date |
May 08, 2017 |
| Contact name |
Yiqiang Wang |
| E-mail(s) |
[email protected]
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| Phone |
86-512-88970213
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| Organization name |
Xi'an Jiaotong-Liverpool University
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| Street address |
111 Renai Road
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| City |
Suzhou |
| State/province |
Jiangsu |
| ZIP/Postal code |
215123 |
| Country |
China |
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| Platforms (1) |
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| Samples (15)
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| GSM949212 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P8, replicate 1 |
| GSM949213 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P8, replicate 2 |
| GSM949214 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P8, replicate 3 |
| GSM949215 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P12, replicate 1 |
| GSM949216 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P12, replicate 2 |
| GSM949217 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P12, replicate 3 |
| GSM949218 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P13, replicate 1 |
| GSM949219 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P13, replicate 2 |
| GSM949220 |
Retina of WT C57BL/6J vs. RNV of OIR C57BL/6J, P13, replicate 3 |
| GSM949221 |
Retina of P9 WT C57BL/6J vs. RNV of P13 OIR C57BL/6J, replicate 1 |
| GSM949222 |
Retina of P9 WT C57BL/6J vs. RNV of P13 OIR C57BL/6J, replicate 2 |
| GSM949223 |
Retina of P9 WT C57BL/6J vs. RNV of P13 OIR C57BL/6J, replicate 3 |
| GSM949224 |
P9 vs. P30 retina of WT C57BL/6J, replicate 1 |
| GSM949225 |
P9 vs. P30 retina of WT C57BL/6J, replicate 2 |
| GSM949226 |
P9 vs. P30 retina of WT C57BL/6J, replicate 3 |
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| Relations |
| BioProject |
PRJNA168565 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE38762_RAW.tar |
86.4 Mb |
(http)(custom) |
TAR (of GPR) |
| Processed data included within Sample table |
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