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| Status |
Public on Sep 01, 2013 |
| Title |
Expression profiling of prostate cell lines by miRNA array |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Prostate cancer (PCa) is the most common malignant carcinoma that develops in men in Western countries. Up to 30% of patients continue to suffer from disease progression following radical prostatectomy. Therefore, better prognostic markers and molecular targets for cancer treatment are needed. MicroRNA (miRNA) has the potential to be used as biomarkers and as a therapeutic target for the treatment of various cancers, including PCa. Here, to determine how miRNA is involved in PCa progression, we investigated the miRNA expression profiles of 3 PCa cell lines, namely PC3, DU145, and LNCaP, and 2 normal prostate cell lines, namely RWPE-1 and PrSc, using miRNA microarrays.
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| Overall design |
We investigated miRNA genes that were significantly upregulated in PCa cell lines (PC3, DU145, LNCaP) compared with normal cell lines (RWPE-1, PrSc).
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| Contributor(s) |
Kobayashi N, Uemura H, Nagahama K, Okudela K, Furuya M, Ino Y, Ito Y, Hirano H, Inayama Y, Aoki I, Nagashima Y, Kubota Y, Ishiguro H |
| Citation(s) |
23231923 |
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| Submission date |
Aug 09, 2012 |
| Last update date |
Dec 02, 2013 |
| Contact name |
Satoshi Kondo |
| Organization name |
Toray Industries,Inc.
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| Department |
New Projects Development Division
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| Street address |
Tebiro 6-10-1
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| City |
Kamakura |
| State/province |
Kanagawa |
| ZIP/Postal code |
248-8555 |
| Country |
Japan |
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| Platforms (1) |
| GPL10312 |
3D-Gene Human miRNA Oligo chip v12-1.00 |
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| Samples (5)
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| Relations |
| BioProject |
PRJNA172406 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE40026_RAW.tar |
360.0 Kb |
(http)(custom) |
TAR (of GPR) |
| Processed data included within Sample table |
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