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| Status |
Public on Apr 01, 2013 |
| Title |
The effect of knock-down of neuroblastoma associated lncRNA on transcriptome |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
As part of functional characterization of neuroblastoma associated lncRNA HOXD-AS1, we performed its knock-down in neuroblastoma cell line SH-SY5Y, which resulted in modulation of expression levels of a set of genes involved in angiogenesis and inflammation, the hallmarks of metastatic cancer.
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| Overall design |
SH-SY5Y cells were transfected with non-targeting siRNA control and two siRNAs targeting lncRNA HOXD-AS1. Two days after transfection total RNA was isolated and hybridized to microarray, each sample was done in four replicas.
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| Contributor(s) |
Yarmishyn AA, Batagov AO, Kurochkin IV |
| Citation(s) |
25522241 |
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| Submission date |
Sep 07, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Aliaksandr A Yarmishyn |
| E-mail(s) |
[email protected]
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| Phone |
+886908866259
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| Organization name |
Taipei Veterans General Hospital
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| Street address |
No. 201, Section 2, Shipai Road, Beitou District
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| City |
Taipei |
| ZIP/Postal code |
11217 |
| Country |
Taiwan |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA174606 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE40680_RAW.tar |
26.2 Mb |
(http)(custom) |
TAR |
| GSE40680_non_normalized.txt.gz |
2.3 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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