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Series GSE4261

Query DataSets for GSE4261

Status

Public on Jul 15, 2006

Title

Antagonism between two mechanisms of antifungal drug resistance

Organism

Saccharomyces cerevisiae

Experiment type

Expression profiling by array

Summary

Genome-wide assays to test the interaction between two independently evolved mechanisms of fluconazole resistance
Keywords: Comparative genomic hybridization

Overall design

Three populations at 100 and 400 generations of evolution in increasing concentrations of fluconazole [experiment 1 - (Anderson et al.,2003 Genetics,163:1287-98, PMID: 12702675, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=12702675)], a single double-mutant (progeny strain from each of the three crosses of the strains from generation 100, and the erg3r mutant strain, were all assayed for gene expression against sce13 the ancestor strain.

Contributor(s)

Anderson JB, Sirjusingh CS

Citation(s)

16896209

Submission date

Feb 17, 2006

Last update date

Mar 16, 2012

Contact name

James B Anderson

E-mail(s)

[email protected]