|
| Status |
Public on Apr 27, 2013 |
| Title |
Analysis of the effects of the methyltransferase encoded by Rv3263 on gene expression in M. tuberculosis |
| Organism |
Mycobacterium tuberculosis H37Rv |
| Experiment type |
Expression profiling by array
|
| Summary |
DNA methylation affects gene expression in many organisms. To determine to effects of DNA methylation on gene expression in M. tuberculosis, we genetically deleted a predicted DNA methyltransferase encoded by Rv3263 and subjected wildtype, mutant, and complemented strains to global expression analysis.
|
| |
|
| Overall design |
RNA was extracted from triplicate cultures of wildtype, methyltransferase deletion, and complemented strains.
|
| |
|
| Contributor(s) |
Fortune SM, Shell SS |
| Citation(s) |
23853579 |
| |
| Submission date |
Apr 26, 2013 |
| Last update date |
Jul 31, 2013 |
| Contact name |
Scarlet Shell |
| E-mail(s) |
[email protected]
|
| Organization name |
Worcester Polytechnic Institute
|
| Department |
Biology and Biotechnology
|
| Lab |
Scarlet Shell
|
| Street address |
60 Prescott St
|
| City |
Worcester |
| State/province |
MA |
| ZIP/Postal code |
01605 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17082 |
[MTbH37Rva520730F] Affymetrix Mycobacterium tuberculosis H37Rv |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA200321 |
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