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Series GSE469 Query DataSets for GSE469
Status Public on Jul 16, 2003
Title Temporal profiling in muscle regeneration.
Organism Mus musculus
Experiment type Expression profiling by array
Summary Temporal expression profiling was utilized to define transcriptional regulatory pathways in vivo in a mouse muscle regeneration model. Potential downstream targets of MyoD were identified by temporal expression, promoter data base mining, and gel shift assays; Slug and calpain 6 were identified as novel MyoD targets. Slug, a member of the snail/slug family of zinc finger transcriptional repressors critical for mesoderm/ectoderm development, was further shown to be a downstream target by using promoter/reporter constructs and demonstration of defective muscle regeneration in Slug null mice.
Keywords: other
 
 
Contributor(s) Zhao P, Iezzi S, Carver E, Dressman D, Gridley T, Sartorelli V, Hoffman EP
Citation(s) 12023284, 25313409
Submission date Jun 26, 2003
Last update date Oct 01, 2019
Contact name Eric P Hoffman
E-mail(s) [email protected]
Organization name Binghamton University - SUNY
Department Pharmaceutical Sciences
Street address PO Box 6000
City Binghamton
State/province NY
ZIP/Postal code 13902
Country USA
 
Platforms (2)
GPL32 [MG_U74A] Affymetrix Murine Genome U74A Array
GPL81 [MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Samples (66)
GSM4246 MuscleRegen-con8wk-1RLA-s2
GSM4247 MuscleRegen-con8wk-1RLAv2-s2
GSM4248 MuscleRegen-con8wk-2LLA-s2
Relations
BioProject PRJNA85083

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE469_RAW.tar 214.6 Mb (http)(custom) TAR (of CEL)

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