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| Status |
Public on Dec 31, 2006 |
| Title |
Gene expression profile of nickel-stimulated HUVEC |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Nickel compounds, important carcinogens and prime inducers of contact allergy in humans, are potent activators of endothelial cells (ECs). To elucidate the signaling pathways mediating the cellular responses to nickel we performed Affymetrix gene profiling of human primary ECs.
Keywords: stress response
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| Overall design |
HUVEC cultured under standard conditions were treated for 5h with 1.5 mM NiCl2 or left untreated before total RNA isolation and processing for microarray hybridization. Four independent experiments were performed, i.e. 8 samples (Control and experiment) were analyzed.
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| Contributor(s) |
Viemann D, Schmidt M, Tenbrock K, Schmidt S, Müller V, Klimmek K, Ludwig S, Roth J, Goebeler M |
| Citation(s) |
17312168 |
| |
| Submission date |
May 16, 2006 |
| Last update date |
Aug 10, 2018 |
| Contact name |
Dorothee Viemann |
| E-mail(s) |
[email protected]
|
| Phone |
+49-511-532 - 7823
|
| Organization name |
Hannover Medical School
|
| Department |
Department of Pediatric Pulmonology, Allergy and Neonatology
|
| Street address |
Carl-Neuberg-Straße 1
|
| City |
Hannover |
| State/province |
Deutschland |
| ZIP/Postal code |
30625 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA95849 |
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