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| Status |
Public on Jun 06, 2007 |
| Title |
Gene expression profiling of circulating plasma RNA from colorectal cancer patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Gene expression profiling of circulating plasma RNA is a valuable tool to detect cancer and a potential clinical instrument to study tumor progression and therapy responsiveness. In this study, differential gene expression analysis was used to identify genes specifically increased in cancer patients.
Keywords: Disease state analysis
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| |
|
| Overall design |
We have measured the relative abundance of the different RNA species in plasma through cDNA microarray hybridization, by comparing RNA isolated and amplified from colorectal cancer patients (12) and from healthy donors (8). Each sample was competitively hybridized against a common reference formed by a pool of blood samples from 26 healthy donors.
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| |
|
| Citation(s) |
17717129 |
| |
| Submission date |
Jun 06, 2006 |
| Last update date |
Jan 20, 2013 |
| Contact name |
Luis LOMBARDIA |
| E-mail(s) |
[email protected]
|
| Organization name |
CNIO (Spanish National Cancer Center)
|
| Department |
Molecualr Pathology Programme
|
| Lab |
Molecular Diagnostics Unit
|
| Street address |
Melchor Fernandez Almagro, 3
|
| City |
MADRID |
| State/province |
Madrid |
| ZIP/Postal code |
28029 |
| Country |
Spain |
| |
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| Platforms (1) |
|
| Samples (20)
|
| GSM112207 |
Colorectal cancer patient SC11_vs_Pool |
| GSM112208 |
Colorectal cancer patient SC6_vs_Pool |
| GSM112299 |
Colorectal cancer patient SC5_vs_Pool |
|
| Relations |
| BioProject |
PRJNA95493 |
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