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| Status |
Public on Nov 09, 2015 |
| Title |
Genomic localization of Cockayne syndrom B protein upon genotoxic stresses |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Cockayne syndrome is an inherited premature aging syndrome associated with developmental and neurological disorders. Mutations in the genomic locus encoding CSB are associated with 80% Cockayne syndrome cases. CSB is invovled in relieving UV-induced and oxidative stree. To gain more insights into the fucntion of CSB under these stress, we use ChIP-seq to determine the genomic localization of CSB 1 hour after UV irradiation and menadione treatment.
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| |
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| Overall design |
Genomic localization of CSB and remodeling deficient CSB∆N1
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| |
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| Contributor(s) |
Jeong J, Won K, Lake R, Boetefuter E, Tsai P, Fan H |
| Citation(s) |
26578602 |
| |
| Submission date |
Sep 17, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Jieun Jeong |
| E-mail(s) |
[email protected]
|
| Organization name |
The University of Pennsylvania
|
| Street address |
3400 Civic Center Blvd
|
| City |
Philadelphia |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA219382 |
| SRA |
SRP029973 |
