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| Status |
Public on Nov 14, 2013 |
| Title |
Expression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
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| Summary |
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes.
The mutants analyzed in this study are further described in Di Chen, Patrick Wai-Lun Li, Benjamin A. Goldstein, Waijiao Cai, Emma Lynn Thomas, Fen Chen, Alan E. Hubbard, Simon Melov and Pankaj Kapahi, Germline Signaling Mediates the Synergistically Prolonged Longevity by Double Mutations in daf-2 and rsks-1 in C. elegans, Cell Reports (CELL-REPORTS-D-13-00388).
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| Overall design |
A 47 chip study using total RNAs from C. elegans wild-type N2 (9 replicates), rsks-1 mutant (9 replicates), daf-2 mutant (9 replicates), daf-2 rsks-1 double mutant (10 replicates) and daf-16; daf-2 rsks-1 triple mutant (10 replicates) measured gene expression levels at the whole genome level.
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| Contributor(s) |
Di C, Pankaj K, Simon M |
| Citation(s) |
24332851 |
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| Submission date |
Nov 13, 2013 |
| Last update date |
Feb 13, 2014 |
| Contact name |
Di Chen |
| Organization name |
Nanjing University
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| Department |
Model Animal Research Center
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| Street address |
12 Xuefu Rd, Pukou
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| City |
Nanjing |
| State/province |
Jiangsu |
| ZIP/Postal code |
210061 |
| Country |
China |
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| Platforms (1) |
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| Samples (47)
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| Relations |
| BioProject |
PRJNA227451 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE52340_RAW.tar |
115.5 Mb |
(http)(custom) |
TAR (of PAIR) |
| Processed data included within Sample table |
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