|
Status |
Public on Apr 05, 2014 |
Title |
Arid1a deletion in collaboration with Pten deletion leads to ovarian tumorigenesis in mouse |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
|
Summary |
Mice developed ovarian tumors after Arid1a and Pten double knockout. Gene expression profiles of 5 such ovarian tumors were compared with those of 4 normal ovaries. The differentially expressed genes were then used to investigate the similarity between the mouse ovarian tumors and major subtypes of human ovarian cancers.
|
|
|
Overall design |
Total RNA obtained from the mouse ovarian tumors developing after Arid1a and Pten knockout compared to normal mouse ovaries.
|
|
|
Contributor(s) |
Guan B, Shih I, Rahmanto YS, Wu R, Wang Y, Wang Z, Wang T |
Citation(s) |
24899687 |
|
Submission date |
Apr 04, 2014 |
Last update date |
Jun 14, 2018 |
Contact name |
Ie-Ming Shih |
Organization name |
Johns Hopkins University School of Medicine
|
Department |
Pathology
|
Street address |
1550 Orleans St. CRB-II, Room 305
|
City |
Baltimore |
State/province |
Maryland |
ZIP/Postal code |
21231 |
Country |
USA |
|
|
Platforms (1) |
GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
|
Samples (9)
|
|
Relations |
BioProject |
PRJNA243644 |