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| Status |
Public on Jul 01, 2014 |
| Title |
Gene expression profiles of neonatal cardiomyocytes and immortalized heart muscle cells exposed to inflammatory stimuli |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
We used a transcriptomic approach to systematically compare the response to inflammatory stimuli for two murine cardiomyocyte models.
Our results indicate that murine neonatal cardiomyocytes (NNC) are able to exhibit a pronounced response upon inflammatory stimuli, while HL-1 cells were predominantly recruiting transcripts corresponding to Jak-Stat-signalling.
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| Overall design |
RNA from murine HL-1 cardiomyocytes and isolated neonatal cardiomyocytes (NNC) stimulated by infectious (PCI) serum or LPS or a cytokine mix (CM) were extracted (n=4 each group) and subjected to microarray analysis for comparison of transcriptomic responses.
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| Contributor(s) |
Lindig S, Stehr SN |
| Citation missing |
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| |
| Submission date |
Apr 08, 2014 |
| Last update date |
Jun 14, 2018 |
| Contact name |
S. Lambeck |
| Organization name |
JUH
|
| Street address |
Erlanger Allee 101
|
| City |
Jena |
| ZIP/Postal code |
07743 |
| Country |
Germany |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (39)
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| Relations |
| BioProject |
PRJNA244001 |
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