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| Status |
Public on May 03, 2014 |
| Title |
Expression data from adult lungs isolated from TMEM100-deficient mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Tmem100 was identified as a downstream gene of BMP9-ALK1 signaling. The signaling has been implicated in hereditary hemorrhagic telangiectasia. This study was designed to identify affected genes in TMEM100-deficiect mice. Tmem100 was inactivated in adult Tmem1002loxP/2loxP;ROSA26+/CreER mice by tamoxifen tereatment. Microarray data was obtained from the lungs isolated from tamoxifen treated control and mutant mice.
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| Overall design |
Three control mice (Tmem1002loxP/2loxP) and three mutant mice (Tmem1002loxP/2loxP;ROSA26+/CreER) were treated with tamoxifen (two consecutive intraperitoneal injections, 0.1 mg/g of body weight) to activate CreER recombinase. Total RNAs were isolated from lungs 7 days after tamoxifen injection.
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| Contributor(s) |
Lee YJ, Oh S, Moon E |
| Citation(s) |
25538155 |
| |
| Submission date |
May 02, 2014 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Young Jae Lee |
| E-mail(s) |
[email protected]
|
| Organization name |
Gachon University
|
| Department |
Lee Gil Ya cancer and Diabetes Institute
|
| Lab |
Developmental Genetics
|
| Street address |
155, Gaetbeol-ro, Yeonsu-gu
|
| City |
Incheon |
| ZIP/Postal code |
406-840 |
| Country |
South Korea |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA246087 |
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