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Series GSE60507 Query DataSets for GSE60507
Status Public on Jan 06, 2015
Title BAC aCGH profiling of 64 GBM (primary & recurrent)
Organism Homo sapiens
Experiment type Genome variation profiling by genome tiling array
Summary aCGH was used to profile copy-number aberrations (CNA) in 64 glioblastoma specimen of patients treated within clinical trials. The data was used to identify changes in CNA which contribute to the aberrant of expression of HOX transcription factors. Our group had previously demonstrated that expression of HOX genes was associated with increased resistance to chemo-radiotherapy and worse outcome in GBM patients Keywords: Disease state comparison
 
Overall design Genomic DNA from the 64 samples and synthetic normal reference DNA were labelled with Cy3 and Cy5 respectively and hybridised to HumArray3 and HumArray2 chips. The unified platform HumArray3.1 is used for annotation purposes
 
Contributor(s) Kurscheid S, Bady P, Hamou M, Diserens A, Stupp R, Delorenzi M, Hegi ME
Citation(s) 25622821
Submission date Aug 19, 2014
Last update date Jan 29, 2015
Contact name Sebastian Kurscheid
E-mail(s) [email protected]
Organization name Australian National University
Department JCSMR
Lab Prof David Tremethick
Street address 57 Garran Road
City Acton
State/province ACT
ZIP/Postal code 2601
Country Australia
 
Platforms (1)
GPL4421 UCSF HumArray 3.1
Samples (64)
GSM1481347 genomic_DNA_from_Surgical_resection_GBM-1647
GSM1481348 genomic_DNA_from_Surgical_resection_GBM-1297
GSM1481349 genomic_DNA_from_Surgical_resection_GBM-1308
Relations
BioProject PRJNA258443

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE60507_Matrix_signal_intensities.txt.gz 1.6 Mb (ftp)(http) TXT
Processed data included within Sample table
Processed data are available on Series record
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