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| Status |
Public on Oct 03, 2014 |
| Title |
Expression from hemocytes misexpressing Idh-R195H vs. controls |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
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| Summary |
Expression profile for hemocytes from hml-Gal4, UAS-2xEGFP larvae were compared to hemocytes from hml-Gal4, UAS-2xEGFP; UAS-Idh-R195H larvae
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| Overall design |
We sought to determine which genes and pathways were upregulated or downregulated in hemocytes expressing Idh-R195H, the Drosophila homolog of the human cancer-associated IDH1-R132H mutant, in vivo. We sought to obtain homogeneous populations of hemocytes from each genotype. We compared larvae expressing Idh-R195H from the hml-Gal4 driver to larvae with the hml-Gal4 driver alone.
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| Contributor(s) |
Reitman ZJ, Yan H |
| Citation(s) |
25398939 |
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| Submission date |
Oct 02, 2014 |
| Last update date |
May 04, 2018 |
| Contact name |
Zachary J. Reitman |
| E-mail(s) |
[email protected]
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| Phone |
9196133697
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| Organization name |
Duke Univ. Medical Ctr.
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| Department |
Pathology
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| Street address |
159 MSRB1
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| City |
Durham |
| State/province |
NC |
| ZIP/Postal code |
27710 |
| Country |
USA |
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| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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| Samples (6)
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| GSM1518369 |
control hemocytes, biological replicate 1 |
| GSM1518370 |
control hemocytes, biological replicate 2 |
| GSM1518371 |
control hemocytes, biological replicate 3 |
| GSM1518372 |
Idh-R195H hemocytes, biological replicate 1 |
| GSM1518373 |
Idh-R195H hemocytes, biological replicate 2 |
| GSM1518374 |
Idh-R195H hemocytes, biological replicate 3 |
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| Relations |
| BioProject |
PRJNA262929 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE62008_RAW.tar |
11.4 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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