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| Status |
Public on Jan 05, 2015 |
| Title |
Genome-wide analysis of the TEC-specific Hipk2 gene knockout in mouse medullary thymic epithelial cells (mTECs) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of the role of Hipk2 in regulating gene expression in medullary thymic epithelial cells. The whole genome gene signatures of purified mTEC subsets (CD80 low, CD80 high) from TEC-specific Hipk2 knockout mice were compared to mating wildtype control mice (floxed, Cre-). Results provide the up- or down-regulated genes, affected by the Hipk2 gene knockout.
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| |
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| Overall design |
Total RNA obtained from isolated CD80 low and CD80 high mTECs of TEC-specific Hipk2 knockout mice compared to control mice mTEC subsets
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| |
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| Contributor(s) |
Rattay K, Kyewski B |
| Citation(s) |
25552543, 26697330 |
| |
| Submission date |
Nov 18, 2014 |
| Last update date |
Nov 24, 2017 |
| Contact name |
Kristin Rattay |
| E-mail(s) |
[email protected]
|
| Organization name |
German Cancer Research Center
|
| Department |
D090
|
| Lab |
Developmental Immunology
|
| Street address |
Im Neuenheimer Feld 280
|
| City |
Heidelberg |
| ZIP/Postal code |
69120 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL17543 |
Illumina MouseWG-6 v2.0 R2 expression beadchip |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA267718 |
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