|
| Status |
Public on Jan 24, 2015 |
| Title |
Evaluation of covS polymorphisms on group A streptococcal global gene expression |
| Organism |
Streptococcus sp. 'group A' |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We sought to determine how single amino acid changes in the active site of CovS autophosphorylation and subsequent phosphorylation of the response regulator CovR affect the gene expression profile of group A streptococcus
|
| |
|
| Overall design |
There were 6 strains analyzed, each in quadruplicate replicates: 1) wild-type GAS; 2) covS deletion strain; 3) covS with alanine at AA 280; 4) covS with valine at AA 281; 5) covS with valine at AA 284; 6) covS with alanine at AA 457
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| |
|
| Contributor(s) |
Shelburne SA, Horstmann N, Yao H |
| Citation(s) |
25561708 |
| |
| Submission date |
Jan 23, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Samuel Shelburne |
| E-mail(s) |
[email protected]
|
| Phone |
713-792-3629
|
| Organization name |
MD Anderson Cancer Center
|
| Department |
Infectious Diseases
|
| Street address |
1515 Holcombe Blvd
|
| City |
Houston |
| State/province |
TX |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19691 |
Illumina HiSeq 2000 (Streptococcus sp. 'group A') |
|
| Samples (24)
|
|
| Relations |
| BioProject |
PRJNA273454 |
| SRA |
SRP052777 |
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