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| Status |
Public on Jun 30, 2007 |
| Title |
Gene expression changes in BVDV2-infected BL3 cells |
| Organism |
Bos taurus |
| Experiment type |
Expression profiling by SAGE
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| Summary |
The goal of this study was to study the gene expression changes that occurred in BL3 cells that were infected with type 2 bovine viral diarrhea virus (BVDV2). What happens within the cell and how the cell responds to the virus is completely unknown.
Keywords: gene expression changes, BVDV2-infected cells, acute infection
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| Overall design |
This study compared the gene expression patterns in noninfected BL3 cells to that in cells that had been infected with BVDV2 for 18 hours. The 2 SAGE libraries were compared to each other to determine which transcripts were present at altered levels in the infected cells. This data will give clues to how the viral infection gives rise to the different pathologies observed in infected animals.
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| Contributor(s) |
Neill JD, Ridpath JF |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Jan 10, 2007 |
| Last update date |
Mar 16, 2012 |
| Contact name |
John D. Neill |
| E-mail(s) |
[email protected]
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| Phone |
515-663-7730
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| Organization name |
National Animal Disease Center
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| Lab |
VPDLRU
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| Street address |
2300 Dayton Ave.
|
| City |
Ames |
| State/province |
IA |
| ZIP/Postal code |
50010 |
| Country |
USA |
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| Platforms (1) |
| GPL223 |
SAGE:10:NlaIII:Bos taurus |
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| Samples (2) |
| GSM154615 |
Bovine BL3 cells under normal culture conditions |
| GSM154617 |
Bovine BL3 cells acutely infected with BVDV2 strain 296c |
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| Relations |
| BioProject |
PRJNA99019 |
