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| Status |
Public on Feb 16, 2016 |
| Title |
Identification of the gene expression in IPF lung fibroblasts after demethylation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease. Although the pathogenesis is poorly understood, evidence suggests that genetic and epigenetic alterations, such as DNA methylation, may play a key role. We used microarrays to see the gene expression in IPF fibroblasts after demethylation agent 5'-azacytidine treatment.
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| |
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| Overall design |
Human IPF lung fibroblasts were cultured and then treated with 5'-azacytidine 5uM 24 hours. RNA were extracted and hybridized on Affymetrix microarrays.
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| Contributor(s) |
Yang T, Jiang D |
| Citation(s) |
26442443 |
| |
| Submission date |
Jun 10, 2015 |
| Last update date |
Mar 25, 2019 |
| Contact name |
ting Xie |
| Organization name |
Cedars-Sinai Medical Center
|
| Department |
Pulmonary
|
| Street address |
127 San Vicente Blvd
|
| City |
Los Angeles |
| State/province |
CA |
| ZIP/Postal code |
90034 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA286695 |
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