|
Status |
Public on Sep 09, 2015 |
Title |
Association of Taf14 with acetylated histone H3 directs the DNA damage response and gene transcription |
Organism |
Saccharomyces cerevisiae |
Experiment type |
Expression profiling by high throughput sequencing
|
Summary |
We sequenced mRNA from triplicate log-phase cultures of BY4741 (WT) transformed with pRS313-HA3-SSN6 and taf14D transformed with pRS313-HA3-SSN6 (empty vector), full-length pRS313-TAF14-HA3-SSN6, or pRS313-taf14W81A-HA3-SSN6 cultured in synthetic complete media lacking histidine.
|
|
|
Overall design |
Examination of changes in gene expression when the YEATS domain of Taf14 is mutated so it cannot bind acetyl-H3.
|
|
|
Contributor(s) |
Shanle EK, Strahl BD |
Citation(s) |
26341557 |
|
Submission date |
Aug 05, 2015 |
Last update date |
May 15, 2019 |
Contact name |
Erin K Shanle |
E-mail(s) |
[email protected]
|
Organization name |
University of North Carolina at Chapel Hill
|
Department |
Biochemistry and Biophysics
|
Lab |
Brian D. Strahl
|
Street address |
3010 Genetic Medicine, 120 Mason Farm Road
|
City |
Chapel Hill |
State/province |
NC |
ZIP/Postal code |
27599 |
Country |
USA |
|
|
Platforms (1) |
GPL13821 |
Illumina HiSeq 2000 (Saccharomyces cerevisiae) |
|
Samples (12)
|
|
Relations |
BioProject |
PRJNA292038 |
SRA |
SRP062085 |