|
| Status |
Public on Mar 01, 2016 |
| Title |
RNAseq Reveals Virulence-Specific Host Responses to M. tuberculosis infection |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We infect bone marrow derived macrophages (BMDMs) with either a Hyper or Hypovirulent Mycobacterium tuberculolsis strain and assess the host response to these bacteria through RNAseq
|
| |
|
| Overall design |
Uninfected BMDMs served as controls, BMDMs infected with Hypervirulent M.tb (designated R55), BMDMs infected with Hypovirulent m.tb (designated R50). 3 groups with 3 biological replicates, each analysed in triplicate.
|
| |
|
| Contributor(s) |
Leisching GR, Baker B |
| Citation(s) |
27763806 |
| |
| Submission date |
Feb 26, 2016 |
| Last update date |
Jul 30, 2019 |
| Contact name |
Abhilasha Madhvi |
| Organization name |
Stellenbosch University
|
| Street address |
Francie van Zijl Drive. Tygerberg
|
| City |
Bellville |
| State/province |
Western Cape |
| ZIP/Postal code |
7505 |
| Country |
South Africa |
| |
|
| Platforms (1) |
| GPL15907 |
AB 5500xl Genetic Analyzer (Mus musculus) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA313266 |
| SRA |
SRP070885 |
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